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Aging is unavoidable and among the important consequences of age is depletion in the level of your vital hormones. Testosterone therapy curbs normal testicular function, and therefore it is vital to understand shrinkage of the testicles will probably happen with long term use in addition to cause infertility for a man of any age Another common consequence of testosterone therapy contains changes to red blood cells , and any guy getting testosterone therapy should be monitoring often by a medical provider to evaluate treatment response and manage impacts of therapy.

The Xu meta-analysis involved 27 published, randomized, placebo-controlled trials representing 2,994 largely middle-aged and older male participants (1,773 treated with testosterone and 1,261 treated with placebo) who reported 180 cardiovascular-related adverse events.9 This study found that testosterone therapy johanan rand was associated with an increased risk of adverse cardiovascular events (Odds Ratio OR=1.5, 95% CI: 1.1-2.1); yet, methodological problems limit conclusions.

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